ITTP, fetal CD3-CD4+CD8- intrathymic T progenitor cells
DP, fetal CD3intCD4+CD8+ "double positive" thymocytes
SP4, fetal CD3highCD4+CD8- “single positive” thymocytes
TSC, fetal thymic stromal cells
Analysis of CD4+ T cell differentiation by expression profiling of subpopulations of CD4+ cells representing 5 successive stages of differentiation: intrathymic T progenitors, double positive thymocytes, single positive thymocytes, naïve T cells from cord blood, and naïve T cells from adult blood.
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Subpopulations of human fetal thymocyte and circulating naïve T cells were obtained through FACS sorting, including CD3-CD4+CD8- intrathymic T progenitor cells (ITTP), CD3intCD4+CD8+ "double positive" thymocytes (DP), CD3highCD4+CD8- "single positive" thymocytes (SP4), CD3+CD4+CD8-CD45RA+CD62L+ naïve T cells from cord blood (CB4+), and CD3+CD4+CD8-CD45RA+CD62L+ naïve T cells from adult blood (AB4+).
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| Sample ID | !Sample Title | Group name |
|---|---|---|
| GSM24623 | ITTP-1B | ITTP |
| GSM24624 | ITTP-2B | ITTP |
| GSM24625 | ITTP-3B | ITTP |
| GSM24626 | DP-1B | DP |
| GSM24627 | DP-2B | DP |
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| Sample ID | !Sample Title | Group name |
|---|---|---|
| GSM24623 | ITTP-1B |
ITTP |
| GSM24624 | ITTP-2B |
ITTP |
| GSM24625 | ITTP-3B |
ITTP |
| GSM24626 | DP-1B |
DP |
| GSM24627 | DP-2B |
DP |
| GSM24628 | SP4-1B |
SP4 |
| GSM24629 | SP4-2B |
SP4 |
| GSM24630 | SP4-3B |
SP4 |
| GSM24631 | CB4-1B |
CB4+ |
| GSM24632 | CB4-2B |
CB4+ |
| GSM24633 | AB4-1B |
AB4+ |
| GSM24634 | AB4-2B |
AB4+ |
| GSM24635 | AB4-3B |
AB4+ |
| GSM24636 | TSC-1B |
TSC |
| GSM24637 | TSC-2B |
TSC |
| Name | ||
|---|---|---|
| All Samples | Default | View |
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|---|---|
| All Samples |